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  1. Goodnow, Robert A., ‘Reality check: lipid-oligonucleotide conjugates for therapeutic applications’. Expert Opinion on Drug Discovery 2023
  2. Guillory, Xavier et al. ‘Fragment-based Differential Targeting of PPI Stabilizer Interfaces’. Journal of Medicinal Chemistry 2020, 63, 6694-6707.
  3. Huang, Ying; Savych, Olena; Moroz, Yuii; Chen, Yiyun; Goodnow, Robert A. Jr., ‘DNA-encoded library chemistry: amplification of chemical reaction diversity for the exploration of chemical space’. Aldrichimica Acta 2019, 52, 75-87.
  4. Goodnow, Robert Jr, ‘DNA-Encoded Library Technology (DELT) After a Quarter Century.’. SLAS Discovery : Advancing Life Sciences R & D 2018, 23, 385-386.
  5. Goodnow, Robert A. Jr.; Davie, Christopher P., ‘DNA-encoded library technology: a brief guide to its evolution and impact on drug discovery’. Annual Reports in Medicinal Chemistry 2017, 50, 1-15.
  6. Casas-Selves, Matias; Zhang, Andrew X.; et al. ‘Target deconvolution efforts on Wnt pathway screen reveal dual modulation of oxidative phosphorylation and SERCA2’. ChemMedChem 2017, 12, 917-924.
  7. Goodnow, Robert A. Jr; Dumelin, Christoph E.; Keefe, Anthony D., ‘DNA-encoded chemistry: enabling the deeper sampling of chemical space’. Nature Reviews Drug Discovery 2017, 16, 131-147.
  8. Goodnow, Robert A. Jr.; Davie, Christopher P., ‘2015 First Boston Symposium of Encoded Library Platforms’. MedChemComm 2016, 7, 1268-1270.
  9. Tian, Xia; Basarab, Gregory S.; Selmi, Nidhal; Kogej, Thierry; Zhang, Ying; Clark, Matthew; Goodnow, Robert A. Jr., ‘Development and design of the tertiary amino effect reaction for DNA-encoded library synthesis’. MedChemComm 2016, 7, 1316-1322.
  10. Fuller, Nathan; Spadola, Loredana; Cowen, Scott; Patel, Joe; Schönherr, Heike; Cao, Qing; McKenzie, Andrew; Edfeldt, Fredrik; Rabow, Al; Goodnow, Robert, ‘An improved model for fragment-based lead generation at AstraZeneca.’. Drug discovery today 2016, 21, 1272-83.
  11. Satz, Alexander Lee; Cai, Jianping; Chen, Yi; Goodnow, Robert; Gruber, Felix; Kowalczyk, Agnieszka; Petersen, Ann; Naderi-Oboodi, Goli; Orzechowski, Lucja; Strebel, Quentin, ‘DNA Compatible Multistep Synthesis and Applications to DNA Encoded Libraries’. Bioconjugate Chemistry 2015, 26, 1623-1632.
  12. Goodnow, Robert A. Jr.; Editor, ‘A handbook for DNA-encoded chemistry: Theory and applications for exploring chemical space and drug discovery’. 2014, 453 pages.
  13. Goodnow, Robert A. Jr., ‘A brief history of the development of combinatorial chemistry and the emerging need for DNA-encoded chemistry’. Handbook for DNA-Encoded Chemistry 2014, 19-43.
  14. Gillespie, Paul; Pietranico-Cole, Sherrie; Myers, Michael; et al. ‘Discovery of camphor-derived pyrazolones as 11β-hydroxysteroid dehydrogenase type 1 inhibitors’. Bioorganic & Medicinal Chemistry Letters 2014, 24, 2707-2711.
  15. Gillespie, Paul; Goodnow, Robert A.; Saha, Goutam; Bose, Gopal; Moulik, Kakali; Zwingelstein, Catherine; Myers, Michael; Conde-Knape, Karin; Pietranico-Cole, Sherrie; So, Sung-Sau, ‘Discovery of pyrazolo[3,4-d]pyrimidine derivatives as GPR119 agonists’. Bioorganic & Medicinal Chemistry Letters 2014, 24, 949-953.
  16. Jeges, Gyorgy; Meszaros, Tamas; Szommer, Tamas; Kovacs, Jozsef; Nagy, Tamas; Tymoshenko, Dmytro; Fotouhi, Nader; Gillespie, Paul; Kowalczyk, Agnieszka; Goodnow, Robert A. Jr., ‘First synthesis of methyl 2-amino-6-methoxynicotinate using a combination of microwave and flow reaction technologies’. Synlett 2011, 203-206.
  17. Qiao, Qi; Dominique, Romyr; Sidduri, Achyutharao; Lou, Jianping; Goodnow, Robert A. Jr., ‘Efficient synthesis of aryl methyl sulfide derivatives using (methylthio)trimethylsilane as methylthiolation reagent’. Synthetic Communications 2010, 40, 3691-3698.
  18. Hicks, Alexandra; Goodnow, Robert Jr.; Cavallo, Gary; et al. ‘Effects of LTB4 receptor antagonism on pulmonary inflammation in rodents and non-human primates’. Prostaglandins & Other Lipid Mediators 2010, 92, 33-43.
  19. Goodnow, Robert A. Jr.; Hicks, Alexandra; Sidduri, Achyutharao; et al. ‘Discovery of Novel and Potent Leukotriene B4 Receptor Antagonists. Part 1’. Journal of Medicinal Chemistry 2010, 53, 3502-3516.
  20. Jeges, Gyorgy; Nagy, Tamas; Meszaros, Tamas; Kovacs, Jozsef; Dorman, Gyorgy; Kowalczyk, Agnieszka; Goodnow, Robert A., ‘Practical Synthesis of 5-Aryl-3-alkylsulfonyl-phenol and 5-Aryl-3-arylsulfonyl-phenol Libraries’. Journal of Combinatorial Chemistry 2009, 11, 327-334.
  21. Fotouhi, Nader; Gillespie, Paul; Goodnow, Robert Jr., ‘Lead generation: reality check on commonly held views’. Expert Opinion on Drug Discovery 2008, 3, 733-744.
  22. Qiao, Q.; Dominique, R.; Goodnow, R., ‘2,4-Disubstituted-5-acetoxythiazoles: useful intermediates for the synthesis of thiazolones and 2,4,5-trisubstituted thiazoles’. Tetrahedron Letters 2008, 49, 3682-3686.
  23. Hermann, Gesine J.; Annis, Michael C.; Edwards, Peter D.; Corrales, Marta; Diaz, Lucia; Goodnow, Robert A., ‘An efficient synthetic route to novel 3-alkyl- and 3-aryl-4-iodophenols’. Synthesis 2008, 221-224.
  24. Wang, Zhenyu; Li, Shiming; Ferguson, Stephen; Goodnow, Robert; Ho, Chi-Tang, ‘Validated reversed phase LC method for quantitative analysis of polymethoxyflavones in citrus peel extracts’. Journal of Separation Science 2008, 31, 30-37.
  25. Goodnow, Robert A. Jr.; Gillespie, Paul, ‘Hit and lead identification: efficient practices for drug discovery’. Progress in Medicinal Chemistry 2007, 45, 1-61.
  26. Hicks, Alexandra; Monkarsh, Seth P.; Hoffman, Ann F.; Goodnow, Robert Jr., ‘Leukotriene B4 receptor antagonists as therapeutics for inflammatory disease: preclinical and clinical developments’. Expert Opinion on Investigational Drugs 2007, 16, 1909-1920.
  27. Wang, Zhenyu; Jonca, Malgorzata; Lambros, Ted; Ferguson, Stephen; Goodnow, Robert, ‘Exploration of liquid and supercritical fluid chromatographic chiral separation and purification of Nutlin-3-A small molecule antagonist of MDM2’. Journal of Pharmaceutical and Biomedical Analysis 2007, 45, 720-729.
  28. Li, Shiming; Lambros, Ted; Wang, Zhenyu; Goodnow, Robert; Ho, Chi-Tang, ‘Efficient and scalable method in isolation of polymethoxyflavones from orange peel extract by supercritical fluid chromatography’. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2007, 846, 291-297.
  29. Wang, Zhenyu; Li, Shiming; Jonca, Malgorzata; Lambros, Ted; Ferguson, Stephen; Goodnow, Robert; Ho, Chi-Tang, ‘Comparison of supercritical fluid chromatography and liquid chromatography for the separation of urinary metabolites of nobiletin with chiral and non-chiral stationary phases’. Biomedical Chromatography 2006, 20, 1206-1215.
  30. Fotouhi, N.; Gillespie, P.; Goodnow, R. A.; So, S.-S.; Han, Y.; Babiss, L. E., ‘Application and utilization of chemoinformatics tools in lead generation and optimization’. Combinatorial Chemistry & High Throughput Screening 2006, 9, 95-102.
  31. Goodnow, Robert, ‘Industrialization of drug discovery: from target selection through lead optimization Edited by Jeffrey S. Handen’. ChemMedChem 2006, 1, 384.
  32. Goodnow, Robert Alan Jr.; Gillespie, Paul; Bleicher, Konrad, ‘Chemoinformatic tools for library design and the hit-to-lead process: a user’s perspective’. Methods and Principles in Medicinal Chemistry 2005, 23, 381-435.
  33. Gillespie, Paul; Goodnow, Robert A. Jr., ‘The hit-to-lead process in drug discovery’. Annual Reports in Medicinal Chemistry 2004, 39, 293-304.
  34. Le, Kang; Goodnow, Robert A. Jr., ‘A convenient synthesis of 2-(9H-fluoren-9-ylmethoxycarbonylamino)-thiazole-4-carboxylic acid via N-Fmoc-thiourea’. Synthetic Communications 2004, 34, 1891-1895.
  35. Goodnow, Robert A. Jr.; Shao, Hui, ‘N-hydroxysuccinimide, polymer-supported’. e-EROS Encyclopedia of Reagents for Organic Synthesis 2003, 1-3.
  36. Goodnow, R. A. Jr.; Guba, W.; Haap, W., ‘Library design practices for success in lead generation with small molecule libraries’. Combinatorial Chemistry and High Throughput Screening 2003, 6, 649-660.
  37. Goodnow, Robert Jr., ‘Small molecule lead generation processes for drug discovery’. Drugs of the Future 2002, 27, 1165-1180.
  38. Roche, Olivier; Schneider, Petra; Zuegge, Jochen; Guba, Wolfgang; Kansy, Manfred; Alanine, Alexander; Bleicher, Konrad; Danel, Franck; Gutknecht, Eva-Maria; Rogers-Evans, Mark; Neidhart, Werner; Stalder, Henri; Dillon, Michael; Sjoegren, Eric; Fotouhi, Nader; Gillespie, Paul; Goodnow, Robert; Harris, William; Jones, Phil; Taniguchi, Mikio; Tsujii, Shinji; von Saal, Wolfgang; Zimmermann, Gerd; Schneider, Gisbert, ‘Development of a Virtual Screening Method for Identification of “”Frequent Hitters”” in Compound Libraries’. Journal of Medicinal Chemistry 2002, 45, 137-142.
  39. Goodnow, Robert A. Jr., ‘Current practices in generation of small molecule new leads’. Journal of Cellular Biochemistry 2001, 13-21.
  40. Qiao, Qi; So, Sung-Sau; Goodnow, Robert A. Jr., ‘Stereochemical control factors in the Hantzsch thiazole synthesis: a Hammett substitution correlation analysis’. Organic Letters 2001, 3, 3655-3658.
  41. Stephensen, Henrik; Zaragoza, Florencio; Le, Kang; Goodnow, Robert A. Jr., ‘Resin-bound isothiocyanates as intermediates for the solid-phase synthesis of substituted thiophenes’. Solid-Phase Organic Syntheses 2001, 1, 149-157.
  42. Shao, Hui; Zhang, Qiang; Goodnow, Robert; Chen, Li; Tam, Steve, ‘A new polymer-bound N-hydroxysuccinimidyl active ester linker’. Tetrahedron Letters 2000, 41, 4257-4260.
  43. Cheung, Adrian Wai-Hing; Sidduri, Achyutharao; Garofalo, Lisa M.; Goodnow, Robert A. Jr., ‘An unusual solvent effect on the regiochemical outcome (N-9 versus N-7) of guanine glycosylation using Robins’ reagent (2-N-acetyl-6-O-diphenylcarbamoylguanine)’. Tetrahedron Letters 2000, 41, 3303-3307.
  44. Goodnow, Robert A. Jr.; Tam, Steve; Pruess, David L.; McComas, Warren W., ‘Oligomer synthesis and DNA/RNA recognition properties of a novel oligonucleotide backbone analog: glucopyranosyl nucleic amide (GNA)’. Tetrahedron Letters 1997, 38, 3199-3202.
  45. Goodnow, Robert A. Jr.; Richou, Anne-Roberte; Tam, Steve, ‘Synthesis of thymine, cytosine, adenine, and guanine containing N-Fmoc protected amino acids: building blocks for construction of novel oligonucleotide backbone analogs’. Tetrahedron Letters 1997, 38, 3195-3198.
  46. Yan, Lin; Taylor, Carol M.; Goodnow, Robert Jr.; Kahne, Daniel, ‘Glycosylation on the Merrifield Resin Using Anomeric Sulfoxides’. Journal of the American Chemical Society 1994, 116, 6953-4.
  47. Goodnow, Robert A.; Turner, Christopher J., ‘Binding of the neurotoxin diiodo-philanthotoxin-343 (I2-PhTX-343) to lipid vesicles’. Journal of Liposome Research 1993, 3, 123-34.
  48. Silva, Domingos J.; Goodnow, Robert Jr.; Kahne, Daniel, ‘The sugars in chromomycin A3 stabilize the magnesium(2+)-dimer complex’. Biochemistry 1993, 32, 463-71.
  49. Nakanishi, Koji; Goodnow, Robert; Kalivretenos, Aris; Choi, Seok Ki; Fushiya, Shinji; Chiles, Gary; Eldefrawi, Amira; Eldefrawi, Mohyee; Usherwood, Peter, ‘Synthetic and bioorganic studies with philanthotoxin analogs’. Alfred Benzon Symposium 1992, 33, 138-49.
  50. Choi, S. K.; Goodnow, R. A.; Kalivretenos, A.; Chiles, G. W.; Fushiya, S.; Nakanishi, K., ‘Synthesis of novel and photolabile philanthotoxin analogs: glutamate receptor antagonists’. Tetrahedron 1992, 48, 4793-822.
  51. Brundell, P.; Goodnow, R. Jr.; Kerry, C. J.; Nakanishi, K.; Sudan, H. L.; Usherwood, P. N. R., ‘Quisqualate-sensitive glutamate receptors of the locust Schistocerca gregaria are antagonized by intracellularly applied philanthotoxin and spermine’. Neuroscience Letters 1991, 131, 196-200.
  52. Goodnow, R. A. Jr.; Bukownik, R.; Nakanishi, K.; Usherwood, P. N. R.; Eldefrawi, A. T.; Anis, N. A.; Eldefrawi, M. E., ‘Synthesis and binding of [125I2]philanthotoxin-343, [125I2]philanthotoxin-343-lysine, and [125I2]philanthotoxin-343-arginine to rat brain membranes’. Journal of Medicinal Chemistry 1991, 34, 2389-94.
  53. Goodnow, R. A. Jr.; Nakanishi, K.; Sudan, H. L.; Usherwood, P. N. R., ‘Inactivation of a quisqualate-sensitive glutamate receptor by photosensitive analogs of philanthotoxin’. Neuroscience Letters 1991, 125, 62-4.
  54. Bruce, M.; Bukownik, R.; Eldefrawi, A. T.; Eldeerawi, M. E.; Goodnow, R. Jr.; Kallimopoulos, T.; Konno, K.; Nakanishi, K.; Niwa, M.; Usherwood, P. N. R., ‘Structure-activity relationships of analogs of the wasp toxin philanthotoxin: non-competitive antagonists of quisqualate receptors’. Toxicon 1990, 28, 1333-46.
  55. Anis, Nabil; Sherby, Shebl; Goodnow, Robert Jr.; Niwa, Masatake; Konno, Katsuhiro; Kallimopoulos, Thomas; Bukownik, Rudolf; Nakanishi, Koji; Usherwood, Peter, ‘Structure-activity relationships of philanthotoxin analogs and polyamines on N-methyl-D-aspartate and nicotinic acetylcholine receptors’. Journal of Pharmacology and Experimental Therapeutics 1990, 254, 764-73.
  56. Nakanishi, Koji; Goodnow, R.; Konno, K.; Niwa, M.; Bukownik, Rudolph; Kallimopoulos, Thomas A.; Usherwood, Peter; Eldefrawi, Amira T.; Eldefrawi, Mohyee E., ‘Philanthotoxin-433 (PhTX-433), a non-competitive glutamate receptor inhibitor’. Pure and Applied Chemistry 1990, 62, 1223-30.
  57. Goodnow, R. Jr.; Konno, K.; Niwa, M.; Kallimopoulos, T.; Bukownik, R.; Lenares, Deborah; Nakanishi, K., ‘Synthesis of glutamate receptor antagonist philanthotoxin-433 (PhTX-433) and its analogs’. Tetrahedron 1990, 46, 3267-86.
  58. Brackley, P.; Goodnow, R. Jr.; Nakanishi, K.; Sudan, H. L.; Usherwood, P. N. R., ‘Spermine and philanthotoxin potentiate excitatory amino acid responses of Xenopus oocytes injected with rat and chick brain RNA’. Neuroscience Letters 1990, 114, 51-6.
  59. Konno, K.; Goodnow, Robert; Bukownik, R.; Kallimopoulos, T.; Nakanishi, K.; Eldefrawi, A. T.; Eldefrawi, M. E.; Usherwood, P. N. R.; Mansour, A., ‘Structure and synthesis of philanthotoxin. A potent glutamate receptor antagonist in wasp venom’. Tennen Yuki Kagobutsu Toronkai Koen Yoshishu 1989, 31, 380-7.
  60. Kenny, Peter T. M.; Goodnow, Robert A. Jr.; Konno, Katsuhiro; Nakanishi, Koji, ‘Philanthotoxins. A mass spectrometric investigation’. Rapid Communications in Mass Spectrometry 1989, 3, 295-7.